To gain insight into the cellular and molecular cues that promote neurovascular co-patterning at the earliest stages of human embryogenesis. we developed a human embryonic stem cell model to mimic the developing epiblast. Contact of ectoderm-derived neural cells with mesoderm-derived vasculature is initiated via the neural crest (NC). not the neural tube (NT). https://www.jmannino.com/quick-save-Arcade-Smokey-Bear-Belt-p10222-great-pick/